serum glutathione levels Effects of the M. sylvestris extract on the reduced Serum Glutathione peroxidase level in

Epigenetic regulation of drug resistance In the epigenetic regulatory network of gemcitabine resistance, long noncoding RNA (lncRNA) mediated RRM2 regulation and dynamic regulation of drug-metabolizing enzymes by m 6 A (N6-methyladenosine) methylation modification are two key mechanisms that together constitute a complex resistance network: In the mechanism of gemcitabine resistance, oncogenic lncRNAs (such as MALAT1 and NEAT1) significantly promote the expression of ribonucleotide reductase M2 (RRM2) through epigenetic regulation (Wang et al., 2021)

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J NSC 26 : 1204312054